Extreme heterogeneity in intercourse chromosome differentiation and dosage payment in livebearers
Edited by David M. Hillis, The University of Texas at Austin, Austin, TX, and authorized 6, 2019 (received for review April 1, 2019 august)
Significance
Morphologically and chromosomes have actually over and over repeatedly developed over the tree of life. Nevertheless, the level of differentiation between your intercourse chromosomes differs considerably across types. As intercourse chromosomes diverge, the Y chromosome gene task decays, making genes in the intercourse chromosomes paid off to just one practical content in men. Mechanisms have actually developed to pay because of this lowering of gene dosage. Right right Here, we perform a relative analysis of intercourse chromosome systems across poeciliid species and discover extreme variation in the amount of intercourse chromosome differentiation and Y chromosome degeneration. Also, we find proof for a situation of chromosome-wide dosage compensation in seafood. Our findings have actually crucial implications for intercourse chromosome regulation and evolution.
As soon as recombination is halted between your X and Y chromosomes, sex chromosomes commence to differentiate and transition to heteromorphism. Because there is a remarkable variation across clades within the level of intercourse chromosome divergence, much less is famous in regards to the variation in intercourse chromosome differentiation within clades. right Here, we combined whole-genome and sequencing that is transcriptome to characterize the dwelling and preservation of intercourse chromosome systems across Poeciliidae, the livebearing clade which includes guppies. We discovered that the Poecilia reticulata XY system is significantly over the age of formerly thought, being shared not only having its sis species, Poecilia wingei, but in addition with Poecilia picta, which diverged approximately 20 million years back.
